Thrive Capital Portfolio: AI Startups Backed by Thrive (2025 Tracker)

Thrive Capital is a New York-based venture firm known for backing transformative companies at the intersection of technology, healthcare, and financial services. Their AI investments span foundational models, biotech, and enterprise AI, positioning them as a key player in the emerging AI landscape.

This tracker highlights Thrive's recent AI investments across categories like generative AI, infrastructure, healthcare, and biotech. Updated regularly to capture new deals and funding rounds.

Thrive Capital AI Portfolio (Live Tracker)

This page is updated monthly. Know a startup we missed? Email us!

Top Thrive Capital–Backed AI Startups (2025)

1. Isomorphic Labs

• Round: $600M Series A (2025)
• Sector: AI Drug Discovery
• What They Do: DeepMind spin-off developing AI-generated drug design for clinical trials.
• Why It Matters: Thrive led one of the largest biotech rounds of 2025 — betting heavily on AI-driven pharma innovation.

2. Lila Sciences

• Round: $200M Seed (2025)
• Sector: Scientific Superintelligence / Autonomous Labs
• What They Do: Building AI systems to autonomously generate hypotheses and run scientific experiments.
• Why It Matters: Represents next-gen "AI doing science" — Thrive is on the frontier of AI-backed R&D.

3. Anthropic

• Round: $3.5B Series E (2025)
• Sector: Foundation Models
• What They Do: Creator of Claude, employing Constitutional AI for scalable LLMs.
• Why It Matters: Thrive’s participation in one of the biggest AI rounds underscores its alignment with core infra builders.

4. ElevenLabs

• Round: $180M Series B (2025)
• Sector: Generative Audio AI
• What They Do: Builds tools for speech synthesis and voice cloning.
• Why It Matters: Thrive co-led this creative-AI bet, investing in the next interface layer of AI.

5. Hugging Face

• Round: $235M Series D (2023)
• Sector: Open Source AI Infrastructure
• What They Do: Hosts open models and collaborative ML tooling.
• Why It Matters: Strategic LP in community-driven AI infra — essential to model democratization.

6. Rogo

• Round: $50M Series B (2025)
• Sector: AI Search for Finance / Bankers
• What They Do: A chatbot for investment banking tasks, used by Moelis, Nomura, Tiger Global.
• Why It Matters: Thrive backs tools that replace high-cost knowledge work — reshaping finance workflows.

7. Shield Technology Partners

• Round: $100M (2025)
• Sector: AI-Enabled IT Services (via Thrive Holdings)
• What They Do: Consolidating MSPs under AI-powered operations.
• Why It Matters: Thrive is deploying AI at scale in service industries through its permanent capital arm.

8. ThriveAI

• Round: $1.2M Pre-Seed (2025)
• Sector: AI Agents for Product Management
• What They Do: Automates PM tasks like tracking feedback and competitor analysis via Slack/MS Teams.
• Why It Matters: Embodies the micro-vertical AI agent trend; Thrive’s name aligns with platform branding.

🛰️ What This Tells Us About Thrive Capital AI Strategy

• AI Meets Biotech & Healthcare: Heavy investments in founding models driving therapeutic and experimental science (Isomorphic, Lila).
• Interface & Agentic Layer: Voice (ElevenLabs) and domain agents (Rogo, ThriveAI) signal vertical-first applications.
• Open Infrastructure Commitment: Hugging Face adds infrastructure cache, not just proprietary models.
• Scaling AI via Services & Operations: Shield AI-backed platforms automate routine work across industries.

Thrive takes a hands-on approach, often co-investing with leading firms like Alphabet, Flagship Pioneering, and a16z.

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