Sequoia Capital Portfolio: AI Startups Backed by Sequoia (2025 Tracker)

From foundation models to legal AI, see which companies this top VC firm is investing in to shape the future of artificial intelligence.

Sequoia Capital Portfolio: AI Startups Backed by Sequoia (2025 Tracker)
Source: Sequoia

As one of the most influential VC firms in tech history, Sequoia’s picks in AI are helping define what comes next.

Whether it’s foundational models, infrastructure layers, or AI-native tools for doctors, lawyers, and developers, their portfolio shows a sharp eye for where AI is heading—and where the next unicorns are forming.

This tracker covers every known AI startup Sequoia has backed in 2024 and 2025. We’ll update it regularly as new funding rounds are announced.

Sequoia Capital AI Portfolio (Live Tracker)

Company Sector Funding Round Amount Raised Year Notes
OpenEvidence Health AI Series A Undisclosed 2025 AI copilot for doctors
Together AI Foundation Models Series B $305M 2025 Co-led with Nvidia & General Catalyst
Perplexity AI AI Search Series B $73.6M 2024 Co-investor with IVP
Harvey Legal AI Series B $80M 2024 AI assistant for legal workflows
Mistral Foundation Models Series A $415M 2024 Frontier LLMs out of Europe
Replit Developer Tools Series B $100M+ 2023 AI-native coding environment
Character.AI Conversational AI Series A $150M 2023 Chatbot platform with viral reach
Dust Agentic AI Tools Seed Undisclosed 2024 Building workspace AI agents
This page is updated monthly. Know a startup we missed? Email us to get it added.

Top Sequoia-Backed AI Startups (2025)

OpenEvidence

  • Round: $210M Series B (2025), Valuation $3.5B (up from $1B)
  • Sector: Healthcare AI – Clinical Decision Tools
  • What They Do: Provides real-time, fully cited answers from peer-reviewed literature; used by ~40% of U.S. physicians across 10K+ hospitals.
  • Why It Matters: Transforms clinical information retrieval—scaling trust and adoption rapidly.

Together AI

  • Round: $305M Series B (2025)
  • Sector: Foundation Models
  • Notes: Co-led with Nvidia & General Catalyst; a major play in the race for next-gen LLMs.

Glean

  • Round: $150M Series F (2025), Valuation $7.2B
  • Sector: AI Enterprise Search
  • What They Do: Builds agentic enterprise search tools; now powering workflows while users are idle.

Harvey

  • Round: $300M Series D (Feb 2025)
  • Sector: Legal AI
  • What They Do: AI-powered assistant for lawyers; helps automate legal workflows.

Profound

  • Round: $35M Series B (Aug 2025)
  • Sector: AI Search Visibility / Marketing
  • What They Do: Helps brands optimize visibility in AI-driven search/answer engines.

OpenRouter

  • Round: $40M Series A (2025)
  • Sector: LLM Connectivity
  • What They Do: Platform bridging AI apps with various LLMs and cloud providers.

Statsig

  • Round: ~ $100M at $1.1B valuation. Acquired by OpenAi
  • Sector: Experimentation / Product Decisioning
  • What They Do: AI-native platform for real-time A/B testing and feature flags.

Rillet

  • Round: Series B ($70M) involvement (2025)
  • Sector: FinTech / AI Accounting
  • What They Do: Automates ledger and accounting tasks via AI; Sequoia participated in the round.

Why Sequoia Bets on These Startups

Sequoia has a pattern: bet early, back hard, and help scale.

  • Vertical-first focus: Tools built for critical jobs—doctors (OpenEvidence), lawyers (Harvey), businesses (Glean), brands (Profound).
  • Foundational bets: Together AI keeps Sequoia in the foundational model race alongside Nvidia.
  • Enterprise efficiency: Investments in Statsig and Rillet reflect doubling down on behind-the-scenes AI for operational scale.
  • Search as backbone: Both Glean and Profound show Sequoia is making strategic plays in the future of information access.

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