Sequoia Capital Portfolio: AI Startups Backed by Sequoia (2026 Tracker)
From foundation models to legal AI, see which companies this top VC firm is investing in to shape the future of artificial intelligence.
As one of the most influential VC firms in tech history, Sequoia’s picks in AI are helping define what comes next.
Whether it’s foundational models, infrastructure layers, or AI-native tools for doctors, lawyers, and developers, their portfolio shows a sharp eye for where AI is heading—and where the next unicorns are forming.
This tracker covers every known AI startup Sequoia has backed in 2024 and 2025. We’ll update it regularly as new funding rounds are announced.
Sequoia Capital AI Portfolio (Live Tracker)
| Glean | Enterprise AI Search | Series F | $150M | 2025 | Agentic enterprise search platform |
| ElevenLabs | Generative Voice AI | Series B | Undisclosed | 2024 | AI voice generation and audio infrastructure |
| OpenRouter | LLM Infrastructure | Series A | $40M | 2025 | Unified API for routing across LLM providers |
| Profound | AI Search Visibility | Series B | $35M | 2025 | Optimizes brand presence in AI-driven search engines |
| Rillet | FinTech / AI Accounting | Series B | $70M | 2025 | AI-native accounting and ledger automation |
| Sierra | Customer Support AI | Seed / Series A | Undisclosed | 2024 | AI agents for enterprise customer service |
This page is updated monthly. Know a startup we missed? Email us to get it added.
Top Sequoia-Backed AI Startups (2025)
OpenEvidence
- Round: $210M Series B (2025), Valuation $3.5B (up from $1B)
- Sector: Healthcare AI – Clinical Decision Tools
- What They Do: Provides real-time, fully cited answers from peer-reviewed literature; used by ~40% of U.S. physicians across 10K+ hospitals.
- Why It Matters: Transforms clinical information retrieval—scaling trust and adoption rapidly.
Together AI
- Round: $305M Series B (2025)
- Sector: Foundation Models
- Notes: Co-led with Nvidia & General Catalyst; a major play in the race for next-gen LLMs.
Glean
- Round: $150M Series F (2025), Valuation $7.2B
- Sector: AI Enterprise Search
- What They Do: Builds agentic enterprise search tools; now powering workflows while users are idle.
Harvey
- Round: $300M Series D (Feb 2025)
- Sector: Legal AI
- What They Do: AI-powered assistant for lawyers; helps automate legal workflows.
ElevenLabs
- Round: Series B (ongoing expansion)
- Sector: Generative Voice AI
- What They Do: High-fidelity AI voice generation used across media, gaming, and enterprise.
Sierra
- Round: Early-stage (2024)
- Sector: Customer Support AI
- What They Do: Autonomous AI agents that resolve customer issues end-to-end.
Profound
- Round: $35M Series B (Aug 2025)
- Sector: AI Search Visibility / Marketing
- What They Do: Helps brands optimize visibility in AI-driven search/answer engines.
OpenRouter
- Round: $40M Series A (2025)
- Sector: LLM Connectivity
- What They Do: Platform bridging AI apps with various LLMs and cloud providers.
Statsig
- Round: ~ $100M at $1.1B valuation. Acquired by OpenAi
- Sector: Experimentation / Product Decisioning
- What They Do: AI-native platform for real-time A/B testing and feature flags.
Rillet
- Round: Series B ($70M) involvement (2025)
- Sector: FinTech / AI Accounting
- What They Do: Automates ledger and accounting tasks via AI; Sequoia participated in the round.
Why Sequoia Bets on These Startups
Sequoia has a pattern: bet early, back hard, and help scale.
- Vertical-first focus: Tools built for critical jobs—doctors (OpenEvidence), lawyers (Harvey), businesses (Glean), brands (Profound).
- Foundational bets: Together AI keeps Sequoia in the foundational model race alongside Nvidia.
- Enterprise efficiency: Investments in Statsig and Rillet reflect doubling down on behind-the-scenes AI for operational scale.
- Search as backbone: Both Glean and Profound show Sequoia is making strategic plays in the future of information access.
- Agentic workflows: Glean, Sierra, and Dust reflect a shift from copilots to autonomous agents.
- AI infrastructure leverage: OpenRouter and ElevenLabs show Sequoia’s continued focus on picks-and-shovels layers.
Related Investor Trackers
- a16z AI Portfolio: Startups Backed by Andreessen Horowitz
- NVentures Portfolio: AI Startups Backed by Nvidia
- Thrive Capital Portfolio: AI Startups Backed by Thrive
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