a16z’s AI Portfolio: Startups Backed by Andreessen Horowitz (2025 Tracker)

Andreessen Horowitz (a16z) is one of the most aggressive backers in the AI space. See which AI startups they've funded - and the verticals they’re doubling down on.

a16z’s AI Portfolio: Startups Backed by Andreessen Horowitz (2025 Tracker)
Source: a16z

Last updated: [June, 2025]


This live tracker covers the top artificial intelligence startups funded by a16z in 2025. From chips to copilots, foundation models to open-source tooling, Andreessen Horowitz is everywhere AI is heating up.


🧠 About a16z & Their AI Thesis

From foundational bets like OpenAI (way back when) to leading late-stage rounds for next-gen platforms, the firm has made AI central to its strategy.

Marc Andreessen’s famous “Software is eating the world” now has a sequel: “AI is eating software.”


Category Notable Startups Latest Deal Trend Insight
Foundation Models / GenAI Thinking Machines Lab ~$2B (2025) a16z leads mega-rounds even pre-product, signaling conviction in new AI giants
Copilots (Vertical AI) Cursor, Harvey Cursor – $625M (Feb 2025) Expert-facing copilots scale faster than horizontal tools
AI Hardware & Infra Groq $640M Series D (Aug 2024) a16z is backing chips to break Nvidia’s stranglehold
Voice & Interface Layer ElevenLabs $180M (2025) Voice + multimodal = next-gen user interface
Healthcare AI Hippocratic, Ambience Healthcare Ambience – $243M Series C (2025) Healthcare AI is maturing fast with clinical & coding automation
Clinical Workflow AI Abridge, Tennr Abridge – $150M (2025) Hospital-ops automation = trillion-dollar TAM
Customer-Experience Agents Decagon $45M (2025) AI agents drive down CX costs while boosting service quality
Creative AI / Video Hedra $32M Series A (2025) Omnimodal characters show AI’s push into creator infrastructure
Interactive Media AI Rumi Labs $4.7M pre-seed (2025) a16z is testing early bets on interactive content & entertainment
Logistics AI HappyRobot $44M Series B (2025) AI agents are infiltrating freight ops — a16z broadens verticals
Performance Assist (Prosumer) Cluely $15M (2025) “AI superpowers” for individuals thrive on viral growth loops
Deals pulled from SEC filings + press releases.
Know a startup we missed? or an unannounced a16z AI term sheet? Give us a tip to get it added: Email us

Top a16z-Backed AI Startups (2025)

1. Thinking Machines Lab

  • Round: ~$2B (2025)
  • Valuation: $12B
  • Sector: Foundation Models / GenAI
  • What They Do: Early-stage AI lab led by ex–OpenAI CTO Mira Murati.
  • Why It Matters: Massive raise pre-product. a16z is betting on new AI giants from day one.

2. Cursor

  • Round: $625M (Feb 2025)
  • Valuation: $9.6B
  • Sector: AI Copilot for Developers
  • What They Do: A natural language interface for writing, refactoring, and debugging code
  • Why It Matters: a16z joined Thrive as a lead. Cursor is becoming the go-to dev tool for AI-powered coding, making it one of the highest-valued vertical copilots in the space.

3. Groq

  • Round: $640M Series D (Aug 2024)
  • Valuation: $2.8B
  • Sector: AI Chips / Hardware
  • What They Do: Building custom AI chips and hardware optimized for LLM inference
  • Why It Matters: Co-led by a16z and BlackRock. Groq is one of the few companies tackling the GPU bottleneck head-on with next-gen silicon.

4. ElevenLabs

  • Round: $180M (2025)
  • Sector: Voice AI / GenAI
  • What They Do: AI-powered speech synthesis and voice cloning
  • Why It Matters: a16z co-led this round. Voice is fast becoming a key interface, and ElevenLabs is leading the charge with creator-ready tools and enterprise-grade accuracy.

5. Hippocratic AI

  • Round: $141M Series B (2025)
  • Sector: Healthcare AI Agents
  • What They Do: Safe, non-diagnostic AI agents for patient-facing use cases
  • Why It Matters: a16z is a participating investor. Their involvement in Hippocratic highlights growing conviction in high-trust, regulated AI applications — especially in healthcare.

6. Harvey

  • Round: $300M Series D (2025)
  • Sector: Legal AI / Enterprise
  • What They Do: AI co-pilot for lawyers
  • Why It Matters: a16z joined other top-tier funds like Sequoia and Kleiner Perkins. This signals a16z’s belief in vertical copilots, especially in high-stakes industries like law.

7. Ambience Healthcare

  • Round: $243M Series C (2025)
  • Sector: Healthcare AI / Medical Scribe
  • What They Do: Ambient transcription + coding automation across 40+ health systems.
  • Why It Matters: a16z doubling down on regulated healthcare AI with enterprise adoption.

8. Hedra

  • Round: $32M Series A (2025)
  • Sector: Creative AI / Video Characters
  • What They Do: Omnimodal character models animating video, audio & images.
  • Why It Matters: a16z’s push into AI-powered creator infrastructure.

a16z’s AI Strategy Signals

  • 🏥 Healthcare is the new dev-tools → Ambience, Hippocratic, Abridge, Tennr.
  • 💸 Big, bold bets → From $2B pre-product raises to $600M+ growth rounds.
  • 🔗 Stack coverage → Chips (Groq) → Apps (Cursor, Harvey) → Interfaces (ElevenLabs) → Verticals (Ambience, HappyRobot).
  • 🎬 Beyond SaaS → New wagers in creative AI (Hedra) + interactive media (Rumi Labs).
  • 📈 2025 funding mix → 40% healthcare, 25% infra, 20% vertical copilots, 15% entertainment/logistics

See the pace for yourself: a16z’s 2025 checks leap from coding copilots to clinical ops in under six months.

Follow the dots below, each one’s a fresh term sheet.

Thinking Machines Cursor Ambience ElevenLabs Hedra Hippocratic Harvey Rumi Labs HappyRobot

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