a16z’s AI Portfolio: Startups Backed by Andreessen Horowitz (2025 Tracker)
Andreessen Horowitz (a16z) is one of the most aggressive backers in the AI space. See which AI startups they've funded - and the verticals they’re doubling down on.

Last updated: [June, 2025]
This live tracker covers the top artificial intelligence startups funded by a16z in 2025. From chips to copilots, foundation models to open-source tooling, Andreessen Horowitz is everywhere AI is heating up.
🧠 About a16z & Their AI Thesis
From foundational bets like OpenAI (way back when) to leading late-stage rounds for next-gen platforms, the firm has made AI central to its strategy.
Marc Andreessen’s famous “Software is eating the world” now has a sequel: “AI is eating software.”
Category | Notable Startups | Latest Deal | Trend Insight |
---|---|---|---|
Foundation Models / GenAI | Thinking Machines Lab | ~$2B (2025) | a16z leads mega-rounds even pre-product, signaling conviction in new AI giants |
Copilots (Vertical AI) | Cursor, Harvey | Cursor – $625M (Feb 2025) | Expert-facing copilots scale faster than horizontal tools |
AI Hardware & Infra | Groq | $640M Series D (Aug 2024) | a16z is backing chips to break Nvidia’s stranglehold |
Voice & Interface Layer | ElevenLabs | $180M (2025) | Voice + multimodal = next-gen user interface |
Healthcare AI | Hippocratic, Ambience Healthcare | Ambience – $243M Series C (2025) | Healthcare AI is maturing fast with clinical & coding automation |
Clinical Workflow AI | Abridge, Tennr | Abridge – $150M (2025) | Hospital-ops automation = trillion-dollar TAM |
Customer-Experience Agents | Decagon | $45M (2025) | AI agents drive down CX costs while boosting service quality |
Creative AI / Video | Hedra | $32M Series A (2025) | Omnimodal characters show AI’s push into creator infrastructure |
Interactive Media AI | Rumi Labs | $4.7M pre-seed (2025) | a16z is testing early bets on interactive content & entertainment |
Logistics AI | HappyRobot | $44M Series B (2025) | AI agents are infiltrating freight ops — a16z broadens verticals |
Performance Assist (Prosumer) | Cluely | $15M (2025) | “AI superpowers” for individuals thrive on viral growth loops |
Deals pulled from SEC filings + press releases.
Know a startup we missed? or an unannounced a16z AI term sheet? Give us a tip to get it added: Email us
Top a16z-Backed AI Startups (2025)
1. Thinking Machines Lab
- Round: ~$2B (2025)
- Valuation: $12B
- Sector: Foundation Models / GenAI
- What They Do: Early-stage AI lab led by ex–OpenAI CTO Mira Murati.
- Why It Matters: Massive raise pre-product. a16z is betting on new AI giants from day one.
2. Cursor
- Round: $625M (Feb 2025)
- Valuation: $9.6B
- Sector: AI Copilot for Developers
- What They Do: A natural language interface for writing, refactoring, and debugging code
- Why It Matters: a16z joined Thrive as a lead. Cursor is becoming the go-to dev tool for AI-powered coding, making it one of the highest-valued vertical copilots in the space.
3. Groq
- Round: $640M Series D (Aug 2024)
- Valuation: $2.8B
- Sector: AI Chips / Hardware
- What They Do: Building custom AI chips and hardware optimized for LLM inference
- Why It Matters: Co-led by a16z and BlackRock. Groq is one of the few companies tackling the GPU bottleneck head-on with next-gen silicon.
4. ElevenLabs
- Round: $180M (2025)
- Sector: Voice AI / GenAI
- What They Do: AI-powered speech synthesis and voice cloning
- Why It Matters: a16z co-led this round. Voice is fast becoming a key interface, and ElevenLabs is leading the charge with creator-ready tools and enterprise-grade accuracy.
5. Hippocratic AI
- Round: $141M Series B (2025)
- Sector: Healthcare AI Agents
- What They Do: Safe, non-diagnostic AI agents for patient-facing use cases
- Why It Matters: a16z is a participating investor. Their involvement in Hippocratic highlights growing conviction in high-trust, regulated AI applications — especially in healthcare.
6. Harvey
- Round: $300M Series D (2025)
- Sector: Legal AI / Enterprise
- What They Do: AI co-pilot for lawyers
- Why It Matters: a16z joined other top-tier funds like Sequoia and Kleiner Perkins. This signals a16z’s belief in vertical copilots, especially in high-stakes industries like law.
7. Ambience Healthcare
- Round: $243M Series C (2025)
- Sector: Healthcare AI / Medical Scribe
- What They Do: Ambient transcription + coding automation across 40+ health systems.
- Why It Matters: a16z doubling down on regulated healthcare AI with enterprise adoption.
8. Hedra
- Round: $32M Series A (2025)
- Sector: Creative AI / Video Characters
- What They Do: Omnimodal character models animating video, audio & images.
- Why It Matters: a16z’s push into AI-powered creator infrastructure.
a16z’s AI Strategy Signals
- 🏥 Healthcare is the new dev-tools → Ambience, Hippocratic, Abridge, Tennr.
- 💸 Big, bold bets → From $2B pre-product raises to $600M+ growth rounds.
- 🔗 Stack coverage → Chips (Groq) → Apps (Cursor, Harvey) → Interfaces (ElevenLabs) → Verticals (Ambience, HappyRobot).
- 🎬 Beyond SaaS → New wagers in creative AI (Hedra) + interactive media (Rumi Labs).
- 📈 2025 funding mix → 40% healthcare, 25% infra, 20% vertical copilots, 15% entertainment/logistics
See the pace for yourself: a16z’s 2025 checks leap from coding copilots to clinical ops in under six months.
Follow the dots below, each one’s a fresh term sheet.